Preheat the oven to 350º F (180º C). Generously spray a 12-cup fluted tube cake pan with baking spray. Lightly coat with flour and set aside.
In a large bowl, sift flour, baking powder, baking soda, and salt. Set aside.
In a large bowl or liquid measuring cup, stir together orange juice, milk, and vanilla extract.
In a large bowl, beat the sugar and butter until creamy and pale at medium-high speed, about 3 – 4 minutes. Scrape down the sides and up the bottom of the bowl with a rubber spatula as needed. Add orange zest and mix until for 2 minutes.
Reduce speed to low and mix half of the flour mixture until just combined. Add wet ingredients mixture in three additions, scraping down the mixing bowl with a spatula, and turn the batter over several times to ensure all ingredients are well incorporated. Add the remaining half of the flour; beat just until combined. Do not overmix the batter.
Pour the cake mixture into the prepared pan. Bake for 55 - 65 minutes, or until a skewer comes out clean when poked in the center.
Once done, remove from the oven and allow it to cool for 20-30 minutes inside the pan. Then, invert the slightly cooled bundt cake onto a wire rack or serving dish. Allow to cool completely before slicing.
For the glaze, whisk the confectioners' sugar and orange juice together in a small bowl, adding a little more sugar or orange juice as needed to make a smooth, thick, but pourable glaze. Drizzle over the cooled cake, allowing it to drip down the sides. Transfer to a flat cake plate or cake stand. Serve at room temperature.